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Related Experiment Videos

Evaluation of left ventricular performance using digital subtraction angiography.

M W Kronenberg, R R Price, C W Smith

    The American Journal of Cardiology
    |March 1, 1983
    PubMed
    Summary

    Digital subtraction angiography enhances left ventricular imaging after intravenous or small-volume injections. This technique provides accurate assessments of cardiac performance and anatomy, proving highly useful in clinical practice.

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    Area of Science:

    • Cardiology
    • Radiology
    • Medical Imaging

    Background:

    • Digital subtraction angiography (DSA) shows promise for cardiac applications.
    • Limited studies have correlated DSA with contrast ventriculography.
    • Evaluating left ventricular (LV) function and anatomy with DSA is crucial.

    Purpose of the Study:

    • To assess LV volume, ejection fraction, and regional wall motion using DSA.
    • To compare DSA with conventional contrast ventriculography after intravenous and direct LV injections.
    • To determine the diagnostic quality and correlation of DSA findings.

    Main Methods:

    • DSA was performed after intravenous injection of 40 ml contrast medium.
    • DSA was also evaluated after small-volume (5-10 ml) direct LV injections.

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  • Results were compared with a film-based system using large-volume (40 ml) direct LV injections.

    • Main Results:

    • Intravenous DSA provided diagnostic quality in 9/12 studies.
    • Close correlations were found between intravenous DSA and direct injection for LV ejection fraction (r=0.89) and volume (r=0.91).
    • Small-volume direct LV injection with DSA showed strong correlations for LV ejection fraction (r=0.91) and volume (r=0.96), with 87% regional wall motion correspondence.

    Conclusions:

    • DSA significantly improves left ventricular visibility via intravenous or small-volume direct injection.
    • DSA provides excellent estimates of LV volume and is valuable for studying cardiac performance and anatomy.
    • DSA offers a promising, less invasive alternative for cardiac imaging.