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Abdominal tuberculosis--a disease revived
Annals of the Royal College of Surgeons of England
|March 1, 1983
Summary
Abdominal tuberculosis, once common, has re-emerged in the UK, primarily in immigrants. This resurgence is linked to Mycobacterium tuberculosis hominis, often reactivated years after initial exposure.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Gastroenterology
Background:
- Abdominal tuberculosis was prevalent in the UK until the mid-20th century.
- Improved sanitation, milk pasteurization, and new treatments led to its decline.
- A resurgence has been observed in recent decades, particularly in immigrant populations.
Observation:
- A retrospective review of 68 abdominal tuberculosis cases is presented.
- The study focuses on Mycobacterium tuberculosis hominis, prevalent in immigrants from the Indian subcontinent.
- Cases suggest disease reactivation due to modified immune processes.
Findings:
- The re-emergence of abdominal tuberculosis is primarily associated with Mycobacterium tuberculosis hominis.
- Immigrants may introduce the pathogen, with subsequent reactivation occurring later.
- Differential diagnosis between abdominal tuberculosis and Crohn's disease is crucial.
Implications:
- Understanding the epidemiology of abdominal tuberculosis in immigrant populations is vital.
- Public health strategies may need to address the specific risks in these groups.
- Further research into immune system modifications and disease reactivation is warranted.