[Prevention of radiation-induced skin reactions in breast cancer]

In a controlled study O-(beta-Hydroxyethyl)-rutoside was administered to 31 patients suffering from breast tumor to evaluate the radio-protective effect of the drug. O-(beta-Hydroxyethyl)-rutoside was given intravenously daily before each radiation. Another group of 31 patients served as a control group. Besides subjective symptoms, skin irritations were controlled during the whole treatment period. The results are discussed.