Related Experiment Video
Updated: Aug 16, 2026

Transplantation of Induced Pluripotent Stem Cell-derived Mesoangioblast-like Myogenic Progenitors in Mouse Models of Muscle Regeneration
Published on: January 20, 2014
Muscle regeneration and transplantation enhanced by bone marrow cells
Abstract:
This work was undertaken in an attempt to improve the usually poor results of muscle regeneration and grafting in cases of muscle injury. Since bone marrow cells markedly increase myogenic growth in vitro (in Millipore diffusion chambers), we added autogenous and isologous bone marrow cells to minced muscle grafts or to sites of excised muscle in rats. In each case the opposite side was left without added marrow cells, to serve as a control. The results showed that addition of bone marrow produces more extensive muscle regeneration with little fibrosis. The myogenesis-stimulating and antibacterial properties of bone marrow cells warrant further study, aiming towards clinical application of the method.
More Related Videos
09:17Minimally Invasive Muscle Embedding (MIME) - A Novel Experimental Technique to Facilitate Donor-Cell-Mediated Myogenesis
Published on: August 24, 2017
05:10Improved Methodology for Studying Postnatal Osteogenesis via Intramembranous Ossification in a Murine Bone Marrow Injury Model
Published on: February 7, 2025
Related Concept Videos
Mesenchymal Stem Cells
Whole Body Regeneration
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...
Tissue Transplantation
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...