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[Optimizing conservative urinary calculus expulsion].

D Bach, A Hesse, B Feuereisen

    Fortschritte Der Medizin
    |February 24, 1983
    PubMed
    Summary
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    This study compared conservative treatments for ureteric calculi. Phytotherapeutic medication (Urol) showed comparable stone passage rates to spasmoanalgetic therapy but with fewer side effects and lower costs.

    Area of Science:

    • Urology
    • Pharmacology
    • Nephrology

    Background:

    • Ureteric calculi (kidney stones) are a common condition requiring effective and cost-efficient treatment.
    • Conservative management is often preferred for smaller stones, necessitating a comparison of available therapeutic options.

    Purpose of the Study:

    • To compare the efficacy and safety of a phytotherapeutic agent (Urol) versus traditional spasmoanalgetic therapy for conservative treatment of ureteric calculi.
    • To evaluate stone passage rates, transit time, side effects, and treatment costs.

    Main Methods:

    • A multicentric, randomized, prospective study was conducted.
    • Patients received either classic spasmoanalgetic therapy or Urol medication.
    • Outcomes measured included spontaneous stone passage, transit time, adverse events, and cost-effectiveness.

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    Main Results:

    • Spontaneous stone passage occurred in 85.5% of patients receiving spasmoanalgetic therapy and 89.3% in the Urol group.
    • No significant difference in stone transit time was observed between the two treatment groups.
    • The Urol group experienced fewer side effects and lower treatment costs.

    Conclusions:

    • Phytotherapeutic medication (Urol) offers a comparable efficacy to spasmoanalgetic therapy for conservative ureteric calculi treatment.
    • Urol presents a favorable profile regarding side effects and cost-effectiveness, making it a viable alternative.