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Serum theophylline assay by rate nephelometric inhibition immunoassay: a comparison with high-performance liquid
Therapeutic Drug Monitoring
|January 1, 1983
Abstract:
The reliability of two clinical laboratory methods for assaying theophylline in serum is compared. Analysis of serum-based standards and 70 patient specimens by rate nephelometric inhibition immunoassay (NIIA) and by high-performance liquid chromatography (HPLC) demonstrates that both methods have comparable random analytical variation. The results indicate that NIIA is a reliable method for measuring serum theophylline and may serve as a practical alternative to the HPLC method.