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Updated: Jul 23, 2026

Ovine Lumbar Intervertebral Disc Degeneration Model Utilizing a Lateral Retroperitoneal Drill Bit Injury
Published on: May 25, 2017
Abstract:
Chemonucleolysis is a promising alternative to open surgical treatment of a herniated lumbar disc. The technique involves injecting chymopapain into the disc under fluoroscopic control. Chymopapain is specific for chondromucoprotein in cartilage. The results of chemonucleolysis in 100 patients are reported; the procedure was successful in 83 percent. This closed procedure has a success rate comparable to that of surgery, but has a lower morbidity, is less costly and is more acceptable to patients.
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