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Pathophysiology of schizophrenia.

J R Stevens

    Clinical Neuropharmacology
    |June 1, 1983
    PubMed
    Summary

    Dementia praecox is associated with characteristic convulsive movements of the eyes and speech muscles. These involuntary facial grimaces and oral movements, resembling chorea, are independent of patient thoughts and feelings.

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    Area of Science:

    • Neurology
    • Psychiatry

    Background:

    • Dementia praecox, now known as schizophrenia, presents with a range of neurological and psychiatric symptoms.
    • Convulsive movements, particularly involving facial muscles, are noted in some patients.

    Purpose of the Study:

    • To describe and characterize specific types of convulsive movements observed in dementia praecox.
    • To differentiate these movements from other neurological conditions.

    Main Methods:

    • Observational study detailing the characteristics of convulsive movements.
    • Description of associated facial and oral movements.

    Main Results:

    • Identified characteristic convulsive movements involving eye and speech muscles in dementia praecox.
    • Observed facial grimacing, eye rolling, and mouth distortions resembling choreic movements.
    • Noted associated oral automatisms like lip smacking and tongue clucking, and rapid lip movements.

    Conclusions:

    • The described convulsive movements are a distinct feature of dementia praecox.
    • These movements appear involuntary and independent of the patient's cognitive and emotional state.
    • A peculiar choreiform mouth movement, termed athetoid ataxia, is highlighted.

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