Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Perinatal group B streptococcal infections.

G L Gilbert, S M Garland

    The Medical Journal of Australia
    |June 11, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Early antibiotic therapy improves outcomes for infants with group B streptococcal (GBS) infections. Prophylactic antibiotics are recommended for at-risk mothers and babies, though routine screening and prophylaxis aren't yet established.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Characterisation of Tasmanian leatherwood (Eucryphia lucida) honey according to geographical origin.

    Food chemistry·2025
    Same author

    Exploring the safety and quality of mobile X-ray imaging in a new infectious disease biocontainment unit: an in situ simulation and video-reflexive study.

    BMJ open·2024
    Same author

    Effectiveness of adjunctive rifampicin for treatment of Staphylococcus aureus bacteraemia: a systematic review and meta-analysis of randomized controlled trials.

    The Journal of antimicrobial chemotherapy·2023
    Same author

    Understanding routine (non-outbreak) respiratory protective equipment behaviour of hospital workers in different clinical settings - lessons for the future post-COVID-19.

    The Journal of hospital infection·2023
    Same author

    Experiences of the SARS-CoV-2 pandemic amongst Australian healthcare workers: from stressors to protective factors.

    The Journal of hospital infection·2021
    Same author

    Testing the efficacy and acceptability of video-reflexive methods in personal protective equipment training for medical interns: a mixed methods study.

    BMJ open·2021

    Area of Science:

    • Neonatal infections
    • Pediatric infectious diseases
    • Maternal-fetal medicine

    Background:

    • Group B streptococcal (GBS) infections pose a significant risk to newborns.
    • Early-onset GBS infections can manifest with diverse clinical presentations, from sepsis to asymptomatic bacteremia.
    • Intrauterine infection can occur even with intact membranes and no maternal symptoms.

    Purpose of the Study:

    • To review predisposing factors and clinical presentations of early-onset GBS infections in infants.
    • To assess the impact of antibiotic therapy on outcomes in GBS-infected infants.
    • To evaluate the role of antenatal screening and antibiotic prophylaxis for GBS.

    Main Methods:

    • Retrospective review of 60 infants with early-onset GBS infections.

    Related Experiment Videos

  • Analysis of clinical data, including predisposing factors, presentation, and treatment.
  • Incidence calculation at The Royal Women's Hospital, Melbourne over three years.

    • Main Results:

    • The incidence of GBS infections was 2.0 per 1000 births.
    • Clinical presentations varied widely, including sepsis and asymptomatic bacteremia.
    • Infants who received early antibiotic therapy showed favorable outcomes; none who died had prior treatment.
    • Mothers of affected infants had a high incidence of fever around delivery.

    Conclusions:

    • Early antibiotic therapy is associated with improved outcomes in GBS-infected infants.
    • Prophylactic antibiotic therapy is recommended for high-risk mothers and neonates.
    • The utility of routine antenatal GBS screening and antibiotic or immunoprophylaxis requires further investigation.