Testing of chemicals for mutagenic activity with Schizosaccharomyces pombe

Two genetic end-points are used for testing mutagens in Schizosaccharomyces pombe: forward mutations of the loci which encode steps early in the adenine synthetic pathway and reversion of certain selected mutants. 54 chemicals have been tested for at least one of the genetic end-points. The relevant literature has been reviewed through 1979.