Studies on proteins identical to male and female genital tract secretions

Rabbit seminal plasma and rabbit uterine fluid six days post coitum were used for disc-electrophoretical and immunological studies. With an antiserum, that was partially neutralized with normal rabbit serum and the uterine fluid, in the seminal plasma four groups of antigens could be demonstrated: antigens of type E, occurring in the seminal plasma only, antigens of type EU, occurring in the seminal plasma and the uterine fluid, antigens of type ES, occurring in the seminal plasma and the serum, and antigens of type EUS, occurring in the seminal plasma, the uterine fluid and the serum. Special consideration of the EU-antigen group exhibited five proteins: with biochemical methods four of them could be identified as uteroglobin, seminal plasma acid glycoprotein, a proteinase, and an alkaline phosphatase.