Immunofluorescence study of the distribution of A, B and H cell surface antigens in bladder tumors

The distribution of A, B and H cell surface antigens was studied in 30 patients with bladder tumors using indirect immunofluorescence. These antigens, normally present at the surface of the healthy urothelium, disappear in various degrees in a large number of bladder tumors. Nevertheless, no close correlation exists between this loss of antigens, and the grade and stage of the vesical tumor, although when A, B and H antigens persist the prognosis generally seems better.