[Norbornane compounds in pharmaceutical research]

This review compiles the literature about norbornanes which already are used as medicaments and such bicyclo [2.2.1]heptanes, which are connected with drug research in some way. As is shown for the period from 1967 until 1980 the occupation with these bicyclic compounds has gained some importance in drug research, not only because they are used medicinally but also because they are used as suitable test molecules for studying structure-activity-relationships by reason of their special molecular shape, their voluminous, bicyclic carbon skeleton and the sterically fixed position of their substituents.