[Factors affecting the prognosis of neuroblastomas in children]

A computer analysis of 102 history cases of pediatric neuroblastoma of different localization established certain factors significantly influencing prognosis in this disease. Such factors as treatment modality, stage, patient's age, site and histogenetic pattern of tumor corresponded to the following values of conjugacy coefficient-0.01, 0.02 and 0.05. Treatment modality is of the highest importance. It should be complex and include radiation treatment, surgery and chemotherapy. Radiation treatment (focal dose of not less than 25 Gy) should be supported by combination polychemotherapy. Indications for surgery should be based on stage.