Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gonadotropin excretion and body composition.

R Penny, I P Goldstein, S D Frasier

    Pediatrics
    |February 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Mechanisms of programmed cell death associated to severe dengue in human renal lesions.

    Microbial pathogenesis·2024
    Same author

    Z-scan studies of the nonlinear optical properties of gold nanoparticles prepared by electron beam deposition.

    Applied optics·2016
    Same author

    Cell-mediated immune deficiency in Hodgkin's disease.

    Immunology today·2014
    Same author

    Clinical immunology in Australia.

    Immunology today·2014
    Same author

    Mobile phones, heat shock proteins and cancer.

    Differentiation; research in biological diversity·2001
    Same author

    Long-term therapy with recombinant human growth hormone (Saizen) in children with idiopathic and organic growth hormone deficiency.

    Endocrine·2001

    Changes in body composition correlate with puberty onset in children. Increased body fat and decreased water content accompany rising gonadotropin (FSH and LH) excretion, suggesting hormones drive puberty, not body composition changes.

    Area of Science:

    • Pediatric Endocrinology
    • Human Physiology
    • Reproductive Biology

    Background:

    • Puberty onset involves complex hormonal and physiological changes.
    • The relationship between body composition and pubertal development requires further elucidation.
    • Previous hypotheses suggested body composition changes might trigger puberty.

    Purpose of the Study:

    • To investigate the correlation between urinary gonadotropin excretion and body composition in children.
    • To determine if changes in body composition precede or follow hormonal shifts during puberty.
    • To test the hypothesis that body composition changes trigger puberty.

    Main Methods:

    • Correlated urinary follicle stimulating hormone (FSH) and luteinizing hormone (LH) excretion with total body water (TBW) and body fat (BF) percentages.

    Related Experiment Videos

  • Studied 140 girls and 142 boys aged 3–16 years.
  • Analyzed changes in body composition relative to chronological age and pubertal stage.

    • Main Results:

    • Significant increases in FSH and LH excretion were observed concurrently with increased body fat percentage and decreased total body water percentage in both girls and boys.
    • These pubertal body composition changes occurred at the same chronological age and pubertal stage as increased gonadotropin excretion.
    • Findings indicate that hormonal changes accompany, rather than follow, body composition shifts.

    Conclusions:

    • The study supports the hypothesis that increased gonadotropin and gonadal steroid secretion drive characteristic pubertal changes, including body composition alterations and menarche.
    • The results do not support the hypothesis that changes in body composition initiate increased hypothalamic function and subsequent pubertal events.
    • Hormonal factors are primary drivers of puberty, influencing body composition development.