Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

T- and B-cell memory on mucosal surfaces.

R Ganguly, R H Waldman

    Annals of the New York Academy of Sciences
    |June 30, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Booster immunizations rapidly activate immune cells, enhancing host protection. Memory responses can bridge the gap between systemic and local immunity, depending on antigen delivery.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Deformed graphene FET biosensor on textured glass coupled with dielectrophoretic trapping for ultrasensitive detection of GFAP.

    Nanotechnology·2024
    Same author

    Disorder-to-order transition of long fibers contained in evaporating sessile drops.

    Soft matter·2024
    Same author

    Structural and therapeutic properties of salicylic acid-solubilized Pluronic solutions and hydrogels.

    Soft matter·2024
    Same author

    Pluronic Induced Interparticle Attraction and Re-entrant Liquid-Liquid Phase Separation in Charged Silica Nanoparticle Suspensions.

    Langmuir : the ACS journal of surfaces and colloids·2023
    Same author

    Unusual Growth and Hydration Characteristics of Oil Solubilized Micelles in Aqueous Pluronic Systems.

    The journal of physical chemistry. B·2021
    Same author

    Overt bleeding in complicated P. falciparum malaria: An experience from east coast of India.

    Tropical biomedicine·2021
    Same journal

    Multiomics Profiling During Autoimmune Demyelination Highlights a Complex Regulatory Role for Ataxin-1 in B Cells.

    Annals of the New York Academy of Sciences·2026
    Same journal

    Global Trends in Light Pollution and Their Relationship With Socioeconomic Factors.

    Annals of the New York Academy of Sciences·2026
    Same journal

    Wired for Corruption: Inter-Brain Synchrony Encodes Bribery-Related Value Information and Predicts Bribery Agreement.

    Annals of the New York Academy of Sciences·2026
    Same journal

    LM-YOLO: A Lightweight Multi-Scale Enhanced Model for Forest Smoke Detection Using Unmanned Aerial Vehicles.

    Annals of the New York Academy of Sciences·2026
    Same journal

    Polyrhythm Perception and Production: A Scoping Review.

    Annals of the New York Academy of Sciences·2026
    Same journal

    DARTS-CNN-BiLSTM: Intelligent Fault Diagnosis for Computer Numerical Control Machine Tool Feed System.

    Annals of the New York Academy of Sciences·2026
    See all related articles

    Area of Science:

    • Immunology
    • Vaccinology
    • Mucosal Immunity

    Background:

    • The secretory immune system demonstrates memory capabilities in both B-cell and T-cell populations.
    • Booster immunizations are known to rapidly activate immune lymphocytes, contributing to host defense.
    • Local memory immune responses can be induced by antigen application, whether systemic or at distant mucosal sites.

    Purpose of the Study:

    • To investigate the potential for overcoming the systemic-local immune dichotomy in memory responses.
    • To explore the influence of antigen route and dosage on memory immune responses.

    Main Methods:

    • This study focuses on the immunological memory generated after booster immunization.
    • The research examines the interplay between systemic and mucosal immune compartments.

    Related Experiment Videos

    Main Results:

    • Booster immunization effectively activates immune lymphocytes, suggesting a role in host protection.
    • Local memory responses can be established irrespective of antigen administration site (systemic or mucosal).
    • The route and amount of antigen used for booster immunization can partially bridge the gap between systemic and local immune systems.

    Conclusions:

    • Memory responses in the secretory immune system are robust and involve both B and T cells.
    • Booster immunizations are crucial for rapid immune activation and potential host protection.
    • The route and dosage of antigen are key factors in modulating systemic and local immune memory, offering a way to integrate these responses.