[The role of insulin-dependent cytoplasmic regulator in carbohydrate metabolism during immobilization]

Immobilization decreased the activity of insulin-dependent cytoplasmatic regulator in the rat liver. Cessation of the immobilization resulted in increment of insulin--dependent cytoplasmatic regulator activity in liver and diaphragm. After the immobilization the glycogen content is considerably higher in the liver, which seems to be due to an increase in the regulator activity. The restoration after the immobilization leads to a decrease in hypoglycemic action of insulin in vivo and in insulin-dependent cytoplasmatic regulator action in vitro.