Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nadolol in essential tremor.

W C Koller

    Neurology
    |August 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Nadolol effectively reduced essential tremor in a placebo-controlled study. This benefit was seen in patients previously responsive to propranolol, but not in those who did not respond to propranolol.

    Related Experiment Videos

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Subthalamic deep brain stimulation and impulse control in Parkinson's disease.

    European journal of neurology·2009
    Same author

    A comparison of Parkinson's disease symptoms and self-reported functioning and well being.

    Parkinsonism & related disorders·2008
    Same author

    Topiramate in essential tremor: a double-blind, placebo-controlled trial.

    Neurology·2006
    Same author

    Apolipoprotein E controls the risk and age at onset of Parkinson disease.

    Neurology·2004
    Same author

    Advances in the treatment of Parkinson's disease.

    Drugs of today (Barcelona, Spain : 1998)·2004
    Same author

    Genetic polymorphisms of the N-acetyltransferase genes and risk of Parkinson's disease.

    Neurology·2003
    Same journal

    Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy.

    Neurology·2026
    Same journal

    Blood-Brain Barrier Disruption Before Interhospital Transfer for Thrombectomy and Clinical Outcome.

    Neurology·2026
    Same journal

    At Death's Door: Cytosolic Dopamine in Patients With Parkinson Disease.

    Neurology·2026
    Same journal

    Cerebral Artery Pulsatility, Premorbid Blood Pressure, and Small Vessel Disease on Brain Imaging: A Population-Based Study.

    Neurology·2026
    Same journal

    Genetic Risk for Alzheimer Disease, Midlife Hypertension, and Dementia: The ARIC Neurocognitive Study.

    Neurology·2026
    Same journal

    What is the Relevance of Neuron-Tumor Interactions in Malignant CNS Tumors?

    Neurology·2026
    See all related articles

    Area of Science:

    • Neurology
    • Clinical Pharmacology

    Background:

    • Essential tremor is a common neurological disorder.
    • Beta-blockers are frequently used for essential tremor management.

    Purpose of the Study:

    • To evaluate the efficacy of nadolol in treating essential tremor.
    • To compare nadolol's effectiveness in patients with prior response or non-response to propranolol.

    Main Methods:

    • Placebo-controlled, double-blind study design.
    • Inclusion of patients with essential tremor.
    • Administration of nadolol at 120 mg and 240 mg daily doses.

    Main Results:

    • Nadolol significantly reduced essential tremor at both dosages.
    • A notable treatment effect was observed in patients previously responsive to propranolol.
  • Patients who did not benefit from propranolol did not show significant improvement with nadolol.

    • Conclusions:

    • Nadolol is an effective treatment for essential tremor.
    • Prior response to propranolol may predict a positive response to nadolol.