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Idiopathic hypercalcaemia of chronic dialysis
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association
|January 1, 1983
Abstract:
Three women on different forms of maintenance dialysis developed persistent steroid-responsive idiopathic hypercalcaemia, with low calcium absorption, severe skeletal decalcification, multiple fractures, and severe clinical problems. Bone histology showed osteomalacia with suppression of osteoblast activity and no hyperparathyroidism. The disease persists at least six months after transplantation. The features are compatible with poisoning by a toxin with many similar properties to aluminium: we only found significant aluminium overload in one of these cases.