[Digital subtraction angiocardiography: accuracy of left ventricular volume determination using intravenous injection...

The usefulness and accuracy of intravenous digital subtraction angiography of the left ventricle was proved by comparison with conventional left ventricular angiocardiography. During heart catheterization two cineangiograms were performed in 20 patients at rest: one with direct injection of contrast medium into the left ventricle and the other with intravenous injection. The intravenous angiocardiograms were processed by a hardwired digital image-processing system designed by our own group. Image enhancement was obtained by subtracting a mask image from the contrasted image of the left ventricle. The utility of four different mask modes was examined by correlating end-diastolic and end-systolic volumes determined from conventional and intravenous digital subtraction angiocardiograms of the left ventricle respectively. Reliable quantitative results could only be achieved by obtaining mask and contrasted images from the same phase of the cardiac cycle. Using these special mask modes, the standard deviations of the residuals amounted to +/- 33 and +/- 36 ml respectively. The results show that intravenous digital subtraction angiocardiography allows a quantitative determination of left ventricular volumes at rest.