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Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Peritoneal dialysis for psoriasis: a controlled study.

F C Whittier, D H Evans, P C Anderson

    Annals of Internal Medicine
    |August 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Peritoneal dialysis effectively treated severe psoriasis in a blinded study. Patients undergoing real dialysis showed significant skin clearing, unlike those receiving sham dialysis, indicating its therapeutic potential.

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    Area of Science:

    • Nephrology
    • Dermatology

    Background:

    • Psoriasis is a chronic autoimmune disease affecting skin.
    • Severe psoriasis often requires advanced treatments when conventional therapies fail.

    Purpose of the Study:

    • To evaluate the efficacy of peritoneal dialysis as a treatment for severe, therapy-resistant plaque-type psoriasis.

    Main Methods:

    • A double-blind crossover study design was used.
    • Patients received either real or sham peritoneal dialysis for 4 weeks, followed by observation periods.
    • Treatment involved 48 hours of weekly dialysis with 2-litre exchanges.

    Main Results:

    • Five patients with severe psoriasis were included.
    • Real peritoneal dialysis resulted in complete clearing for two patients and >75% clearing for two others.
    • No patient responded to the sham dialysis procedure (p < 0.01).

    Conclusions:

    • Peritoneal dialysis demonstrates significant efficacy in treating severe plaque-type psoriasis.
    • The positive response to real dialysis, contrasted with sham dialysis, supports its therapeutic role.