Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Red cell deformability.

J A Dormandy

    European Neurology
    |January 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Red blood cell deformability is crucial for circulation and often abnormal in cerebral ischemia. Therapies targeting red blood cell flexibility may offer a new treatment approach for this condition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Thromboelastography.

    Hematology (Amsterdam, Netherlands)·2016
    Same author

    Reprinted article "The fate of the claudicant--a prospective study of 1969 claudicants".

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2011
    Same author

    High-density lipoprotein-cholesterol and not HbA1c was directly related to cardiovascular outcome in PROactive.

    Diabetes, obesity & metabolism·2011
    Same author

    Second European conference on clinical haemorheology.

    Journal of the Royal Society of Medicine·2010
    Same author

    The next 10 years in the management of peripheral artery disease: perspectives from the 'PAD 2009' Conference.

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2010
    Same author

    Impact of peripheral arterial disease in patients with diabetes--results from PROactive (PROactive 11).

    Atherosclerosis·2008
    Same journal

    Combined Olfactory Testing and Substantia Nigra Hyperechogenicity for Diagnostic Differentiation of Parkinson's Disease.

    European neurology·2026
    Same journal

    The Role of Stroke Severity in the Association between Hypoperfusion Intensity Ratio and Futile Reperfusion after Endovascular Treatment.

    European neurology·2026
    Same journal

    The Parkinsonism of Salvador Dalí.

    European neurology·2026
    Same journal

    Disorders of Arousal and Sleep-Related Hypermotor Epilepsy in Adults: A Challenging but Necessary and Critical Distinctive Diagnosis.

    European neurology·2026
    Same journal

    Sex-Specific Phenotypic Characteristics in Obstructive Sleep Apnea: A Comprehensive Analysis of Anthropometric, Hematological, and Metabolic Profiles Stratified by Disease Severity.

    European neurology·2026
    Same journal

    Historical and Clinical Analysis of a Case of Progressive Muscular Atrophy (1853-1871).

    European neurology·2026
    See all related articles

    Area of Science:

    • Hematology
    • Neurology
    • Vascular Biology

    Background:

    • Red blood cell (RBC) deformability is vital for efficient blood circulation.
    • Abnormalities in RBC deformability are implicated in various pathological conditions.
    • Cerebral ischemia is a condition where blood flow to the brain is restricted.

    Purpose of the Study:

    • To investigate the role of red blood cell deformability in cerebral ischemia.
    • To explore filtration techniques for assessing RBC deformability.
    • To evaluate the potential of normalizing RBC deformability as a therapeutic strategy for cerebral ischemia.

    Main Methods:

    • Utilizing filtration techniques to measure red blood cell deformability.
    • Analyzing RBC deformability in patients diagnosed with cerebral ischemia.

    Related Experiment Videos

  • Comparing deformability metrics between healthy individuals and patients.

    • Main Results:

    • Filtration techniques revealed significant red blood cell deformability abnormalities in patients with cerebral ischemia.
    • These abnormalities suggest a link between impaired RBC function and the pathophysiology of cerebral ischemia.
    • The findings highlight the potential diagnostic value of assessing RBC deformability.

    Conclusions:

    • Red blood cell deformability is a critical factor in maintaining normal circulation.
    • Abnormalities in RBC deformability are a key feature in patients suffering from cerebral ischemia.
    • Therapeutic interventions aimed at restoring normal RBC deformability present a promising avenue for treating cerebral ischemia.