Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vascular potential and thrombosis.

J F Stoltz

    Thrombosis Research
    |January 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Negative charges on blood cells and vessel walls influence vascular thrombosis. Electrochemical measurements reveal discrepancies in assessing these charges, impacting our understanding of blood clot formation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Treatment by stem cell therapy of erectile dysfunction of diabetic origin: State of the art].

    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie·2017
    Same author

    Mechanobiology of mesenchymal stem cells: Which interest for cell-based treatment?

    Bio-medical materials and engineering·2017
    Same author

    Aging of bone marrow mesenchymal stromal/stem cells: Implications on autologous regenerative medicine.

    Bio-medical materials and engineering·2017
    Same author

    History and future of hemorheology: From Reykjavik to Lisboa.

    Clinical hemorheology and microcirculation·2016
    Same author

    8th International Meeting of "Lorraine Pole of Cartilage Engineering". Foreword.

    Bio-medical materials and engineering·2014
    Same author

    Innovative treatments for joint diseases. Foreword.

    Bio-medical materials and engineering·2013
    Same journal

    Apoptotic versus procoagulant platelets: similar "necrotic" phenotype and procoagulant activity in vitro, but distinct adhesive protein composition.

    Thrombosis research·2026
    Same journal

    Heatstroke-induced coagulopathy: A scoping review of therapeutic strategies and outcome reporting.

    Thrombosis research·2026
    Same journal

    Mapping thrombus habitat: Non-contrast MRI radiomics and pixel-tile histomics approach to track venous thrombosis evolution in mice.

    Thrombosis research·2026
    Same journal

    A study protocol for a randomised controlled trial evaluating the safety and efficiency of the YEARS algorithm versus computed tomography pulmonary angiography only for suspected acute pulmonary embolism in patients with cancer: the Hydra Study.

    Thrombosis research·2026
    Same journal

    Associating the phenotypic expression of platelets with disease type through image-based single-cell profiling.

    Thrombosis research·2026
    Same journal

    The mechanisms of contractile dysfunction following chronic limited platelet activation in (pro)thrombotic conditions.

    Thrombosis research·2026
    See all related articles

    Area of Science:

    • Biophysics
    • Biochemistry
    • Cardiovascular Science

    Background:

    • Blood cells possess negative charges, crucial for understanding vascular thrombosis.
    • The vessel wall also exhibits negative charges, repelling blood cells and preventing adhesion to the intima.
    • These vascular charges originate from ion/protein adsorption, active transport, and ionized groups.

    Purpose of the Study:

    • To define the importance of electrochemical parameters in vascular thrombosis.
    • To compare different techniques for measuring vascular potential and transmembrane potential.
    • To discuss the role of these charges in thrombosis phenomena.

    Main Methods:

    • Measurement of transmembrane potential using electro-osmosis.
    • Assessment of circulation potential (in vitro and in vivo).

    Related Experiment Videos

  • Comparison of published results with personal research data.
  • Main Results:

    • Transmembrane charge measurements via electro-osmosis and streaming potential show method-dependent discordances.
    • Vascular wall's negative charge plays a role in blood cell repulsion and preventing adhesion.
    • Electrochemical phenomena are integral to understanding vascular thrombosis.

    Conclusions:

    • Electrochemical properties of blood cells and vessel walls are critical in vascular thrombosis.
    • Discrepancies exist in measuring transmembrane charges, necessitating careful method selection.
    • Further research is needed to fully elucidate the role of these charges in preventing thrombosis.