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Related Experiment Videos

Selective posttransplantation bilateral native nephrectomy. Indications and results.

M A Castaneda, P J Garvin, J E Codd

    Archives of Surgery (Chicago, Ill. : 1960)
    |October 1, 1983
    PubMed
    Summary

    Bilateral native nephrectomy after kidney transplant effectively treated erythrocytosis and infections. While hypertension control varied, the procedure offered significant benefits for many patients, improving transplant outcomes.

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    Transplantation proceedings·2002

    Area of Science:

    • Nephrology
    • Transplant Surgery
    • Urology

    Background:

    • Native nephrectomy is a surgical procedure involving the removal of native kidneys.
    • Indications for native nephrectomy post-renal transplantation include complications like uncontrolled hypertension and recurrent infections.

    Purpose of the Study:

    • To evaluate the outcomes of bilateral native nephrectomy in patients who previously received a renal transplant.
    • To assess the efficacy of native nephrectomy in managing specific post-transplant complications.

    Main Methods:

    • Retrospective analysis of 25 patients who underwent bilateral native nephrectomy post-renal transplantation.
    • Indications for surgery included erythrocytosis, recurrent urinary tract infections, and medically uncontrolled hypertension.

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    Main Results:

    • Prompt normalization of hematocrit and red blood cell mass in patients with erythrocytosis.
    • Complete eradication of infection in all patients with recurrent urinary tract infections.
    • Hypertension control was excellent in 6, good in 9, and poor in 4 patients; renin levels did not predict outcomes.

    Conclusions:

    • Bilateral native nephrectomy is an effective treatment for erythrocytosis and recurrent infections in renal transplant recipients.
    • While outcomes for hypertension management are variable, the procedure offers significant benefits for selected patients.
    • Native nephrectomy can be a valuable adjunct in managing complex post-transplant complications.