[Circular dichroism of the complexes between poly-L-lysine and DNA with different GC contents]

Studies were carried out of circular dichroism spectra of the complexes between poly-l-lysine (PL) and calf thymus DNA, E. coli DNA, T2--and T7--phage DNA, Modiolus sp. DNA. The results indicate that PL more strongly changes AT--DNA conformation as compared to GC DNA conformation. This change correlates with the size of minimal PL clusters on DNA investigated. Sequence of DNA bases produces almost no effect on conformational changes caused by the complex-formation with PL.