Accumulation of prolactin in human seminal vesicles as revealed by immunohistochemical studies

The immunoperoxidase technique was used to identify PRL in human seminal vesicles. PRL reactivity was seen as a strong, specific, perivascular staining in the venous plexuses of the invaginations between the folds in the seminal vesicle walls as well as a diffuse staining in the subepithelial stroma. The immunohistochemical staining methods used in this study do not allow any conclusive speculation on the mechanisms by which high concentrations of PRL in the seminal plasma arise, because no distinct cells could be identified as actively producing and secreting PRL by the current techniques.