Pharmacokinetics of bromide ion--an overview

The recent role of bromide as a residue in food and water necessitated its toxicological investigation. Although much was known already about the absorption, distribution and elimination of bromide, more data were required, especially for the rat. The pharmacokinetics in the rat were therefore investigated, with emphasis on cumulation and on the role of chloride in bromide elimination. This review recapitulates old and recent findings on the fate of bromide.