Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Allergic mucociliary dysfunction.

A Wanner

    The Journal of Allergy and Clinical Immunology
    |October 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Allergic airway disease impairs mucociliary transport, worsening with antigen exposure due to chemical mediators. Abnormal secretions also contribute to this dysfunction, impacting allergic rhinitis and asthma management.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Physical activity and the prevention, reduction, and treatment of alcohol and other drug use across the lifespan (The PHASE review): A systematic review.

    Mental health and physical activity·2020
    Same author

    Constraints on cosmic strings from the LIGO-Virgo gravitational-wave detectors.

    Physical review letters·2014
    Same author

    Fast in situ phase and stress analysis during laser surface treatment: a synchrotron x-ray diffraction approach.

    The Review of scientific instruments·2012
    Same author

    Directional limits on persistent gravitational waves using LIGO S5 science data.

    Physical review letters·2012
    Same author

    Integrated Exposure Assessment Survey (INES) exposure to persistent and bioaccumulative chemicals in Bavaria, Germany.

    International journal of hygiene and environmental health·2007
    Same author

    Inhaled corticosteroids: effects on the airway vasculature in bronchial asthma.

    The European respiratory journal·2006
    Same journal

    Corrigendum.

    The Journal of allergy and clinical immunology·2026
    Same journal

    Comparative Efficacy of Biologic Agents for Severe Chronic Rhinosinusitis with Nasal Polyps: A Systematic Review and Network Meta-analysis.

    The Journal of allergy and clinical immunology·2026
    Same journal

    Tamoxifen-driven neutrophil reprogramming protects from pulmonary Granulibacter bethesdensis infection in chronic granulomatous disease.

    The Journal of allergy and clinical immunology·2026
    Same journal

    Clinical and transcriptomic characterization of mixed granulocytic COPD phenotype.

    The Journal of allergy and clinical immunology·2026
    Same journal

    Dupilumab outcomes in pediatric asthma by early eosinophil status: post hoc analysis of VOYAGE/EXCURSION.

    The Journal of allergy and clinical immunology·2026
    Same journal

    Maternal antibiotic exposure alters the newborn metabolomic profile and increases the risk of respiratory infections in offspring: a 13-year longitudinal birth cohort study.

    The Journal of allergy and clinical immunology·2026
    See all related articles

    Area of Science:

    • Pulmonology
    • Allergy and Immunology
    • Respiratory Medicine

    Background:

    • Allergic airway diseases, including asthma and rhinitis, are associated with impaired mucociliary function.
    • Mucociliary dysfunction plays a significant role in the pathophysiology of these conditions.

    Purpose of the Study:

    • To review the impact of allergic airway disease on mucociliary transport.
    • To explore the role of antigen challenge and respiratory secretions in acute allergic mucociliary dysfunction.
    • To evaluate the potential therapeutic strategies for managing allergic mucociliary dysfunction.

    Main Methods:

    • Review of existing studies on mucociliary transport in allergic airway diseases.
    • Analysis of the effects of acute antigen challenge on mucociliary function.

    Related Experiment Videos

  • Examination of the contribution of respiratory secretions to mucociliary dysfunction.

    • Main Results:

    • Mucociliary transport is impaired in the lower airways and potentially the nose in individuals with allergic airway disease.
    • Acute antigen challenge exacerbates mucociliary transport impairment, mediated by chemical factors.
    • Abnormal respiratory secretions are partly responsible for acute allergic mucociliary dysfunction.

    Conclusions:

    • Findings from asthma studies may be applicable to allergic rhinitis.
    • Antiallergic agents like cromolyn sodium and mediator antagonists are justified for managing allergic rhinitis and asthma.
    • Targeting mucociliary dysfunction is crucial for effective management of allergic airway diseases.