Lipoprotein metabolism in liver disease

Liver disease is associated with abnormalities in plasma lipids and lipoprotein structure and metabolism. These abnormalities are not specific for the type of liver disease. The severity of the changes does, however, parallel the severity of the liver disease. Lipoprotein abnormalities may also have prognostic significance; but there is no good correlation between the abnormalities in plasma lipoproteins and more standard liver-function tests. Due to the marked derangements that occur in lipoproteins, liver disease provides a useful model to study lipoprotein metabolism.