[Comparative bacteriostatic activity of 10 cephalosporins against 100 strains of Serratia]

The in vitro activity of 10 cephalosporins was evaluated against 100 different clinical isolates of Serratia. 90% of these strains were inhibited at the following concentrations (microgram/ml): ceftazidime = 0.5; ceftriaxon = 0.9; cefmenoxime = 1; lamoxactam = 1.1; cefotaxime = 1.25; cefotetan = 2; cefoperazone = 28; cefoxitine = 64; cefotiam = 80; ceforanide greater than 512. Ceftazidime was the most potent agent. Ceftriaxon, cefmenoxime, lamoxactam and cefotaxime had also a very high activity. All the strains were clinically susceptible to these 5 cephalosporins (MIC less than or equal to 16). The other cephalosporins were less active.