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Related Experiment Videos

Tranexamic acid and traumatic hyphaema. A prospective study.

P Vangsted, P J Nielsen

    Acta Ophthalmologica
    |June 1, 1983
    PubMed
    Summary

    Tranexamic acid treatment for traumatic hyphaema showed no re-bleeding and was well tolerated. While blood resorption was delayed, this did not cause complications, suggesting treatment efficacy.

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    Area of Science:

    • Ophthalmology
    • Trauma Care

    Background:

    • Traumatic hyphaema, a common ocular injury, poses risks of re-bleeding and vision impairment.
    • Current management often involves conservative measures, but their efficacy in preventing re-bleeding is debated.

    Purpose of the Study:

    • To prospectively investigate the efficacy and safety of tranexamic acid in managing traumatic hyphaema.
    • To compare outcomes between conservative treatment and tranexamic acid administration.

    Main Methods:

    • A prospective study of 112 patients with traumatic hyphaema over 3 years.
    • Patients were divided into conservative treatment (53) and tranexamic acid (59) groups.
    • Both groups received supportive local therapy (glucocorticoids, mydriatics, patching) and were mobilized.

    Main Results:

    • No re-bleeding occurred in either the conservative or tranexamic acid groups.
    • Blood resorption in the anterior chamber was delayed in the tranexamic acid group.
    • This delay did not lead to any complications and the treatment was well tolerated.

    Conclusions:

    • Tranexamic acid is a safe and effective treatment for traumatic hyphaema, with no observed re-bleeding.
    • Delayed blood resorption with tranexamic acid does not appear to be clinically significant.
    • Tranexamic acid has replaced traditional bed rest in clinical practice for this condition.

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