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Neurotrophic protein regulates muscle acetylcholinesterase in culture
Science (New York, N.Y.)
|April 21, 1978
Abstract:
Skeletal muscles lose acetylcholinesterase in culture as a result of denervation. A protein fraction isolated from peripheral nerves maintained the level of acetylcholinesterase in cultures of aneural embryonic muscle or denervated adult chicken muscle. These results indicate that trophic regulation of muscle acetylcholinesterase might be mediated by a protein produced by nerves.