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Related Experiment Videos

Liver transplantation in children.

C E Brölsch, M Burdelski, P Neuhaus

    Zeitschrift Fur Kinderchirurgie : Organ Der Deutschen, Der Schweizerischen Und Der Osterreichischen Gesellschaft Fur Kinderchirurgie = Surgery in Infancy and Childhood
    |February 1, 1983
    PubMed
    Summary

    Pediatric liver transplantation offers good outcomes for children with end-stage liver disease and hepatomas. While challenges like tumor recurrence exist, advancements make liver transplants a viable option for more children.

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    Pediatric transplantation·2013
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    [Living donation liver transplantation in children].

    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2010
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    Cognitive abilities, behaviour and quality of life in children after liver transplantation.

    Pediatric transplantation·2010
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    Effectiveness of Rex shunt in children with portal hypertension following liver transplantation or with primary portal hypertension.

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    Hypogammaglobulinemia in pediatric liver transplant recipients.

    Pediatric transplantation·2005

    Area of Science:

    • Pediatric Hepatology
    • Organ Transplantation
    • Surgical Oncology

    Background:

    • Liver transplantation in children is infrequently performed.
    • Prognosis is acceptable for pediatric end-stage liver disease and unresectable hepatomas.

    Observation:

    • This report details eight pediatric liver transplant cases: five for end-stage cirrhosis, three for hepatoma.
    • One early mortality occurred; others showed remarkable development and rehabilitation.

    Findings:

    • Tumor recurrence is a significant challenge for pediatric hepatoma patients undergoing transplantation.
    • Transplantation for biliary atresia is complicated in late disease stages.
    • Early indication for transplantation necessitates long donor organ waiting times, with potential patient mortality.

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    Implications:

    • Increased experience and improved immunosuppression support broader consideration of liver transplantation for pediatric end-stage liver disease.
    • Liver transplantation is a viable, life-saving option for select pediatric liver conditions.
    • Further research into managing tumor recurrence and optimizing donor organ allocation is warranted.