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Cimetidine-associated depression and loss of libido in a woman

J R Pierce

    The American Journal of the Medical Sciences
    |November 1, 1983
    PubMed

    A healthy young woman developed marked depression and loss of libido while taking cimetidine. Her symptoms promptly resolved after discontinuation of cimetidine suggesting that her symptoms represent an adverse drug reaction. Mental confusion and other neurologic symptoms have been attributed to cimetidine administration, but depression has not been previously reported. This case can not be explained by the presently accepted theory regarding the pathogenesis of cimetidine-associated central nervous system abnormalities.

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