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Evaluation of API microtube GT system for detection of germ tube production by clinically significant yeasts
Journal of Clinical Microbiology
|November 1, 1983
Abstract:
A total of 152 fresh consecutive yeast isolates were tested for their ability to produce germ tubes by the API GT system (Analytab products, Plainview, N.Y.) and by a conventional method. The API system was found to be less sensitive than the conventional method. The costs per test by the API system and the conventional method were $0.76 and $0.39, respectively.
Insights
The API GT system is less sensitive for detecting yeast germ tubes compared to conventional methods. Conventional methods are also more cost-effective for yeast identification.
Area of Science:
- Medical Mycology
- Clinical Microbiology
Background:
- Accurate identification of yeast isolates is crucial in clinical settings.
- Germ tube production is a key preliminary test for yeast identification, particularly for *Candida albicans*.
- Evaluating diagnostic tools for efficiency and cost-effectiveness is essential for laboratory practice.
Purpose of the Study:
- To compare the sensitivity of the API GT system with a conventional method for detecting yeast germ tube production.
- To assess the cost-effectiveness of the API GT system versus the conventional method.
Main Methods:
- A total of 152 fresh yeast isolates were tested.
- Germ tube production was assessed using the API GT system.
- Germ tube production was also assessed using a conventional slide culture method.
Main Results:
- The API GT system demonstrated lower sensitivity in detecting germ tubes compared to the conventional method.
- The cost per test for the API GT system was $0.76.
- The cost per test for the conventional method was $0.39.
Conclusions:
- The conventional method is more sensitive for germ tube detection than the API GT system.
- The conventional method offers a significant cost advantage over the API GT system for this diagnostic test.