Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prosthetic heart valves: a review.

J A McClung, J H Stein, J A Ambrose

    Progress in Cardiovascular Diseases
    |November 1, 1983
    PubMed
    Summary

    The caged ball valve, despite design limitations like central obstruction and large size, remains a durable prosthetic option. Its extensive clinical history provides valuable data for understanding long-term performance in cardiac surgery.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    CYP-450 Epoxygenase Derived Epoxyeicosatrienoic Acid Contribute To Reversal of Heart Failure in Obesity-Induced Diabetic Cardiomyopathy <i>via</i> PGC-1 <i>α</i> Activation.

    Cardiovascular pharmacology: open access·2018
    Same author

    Baseline cardiovascular risk in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial.

    HIV medicine·2015
    Same author

    Effect of statin therapy in reducing the risk of serious non-AIDS-defining events and nonaccidental death.

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2013
    Same author

    Pathophysiology of acute coronary 1-syndromes.

    Platelets·2010
    Same author

    Nicotinic acid and the level of protein intake in the nutrition of the pig.

    The Journal of nutrition·2010
    Same author

    The Use of Manganese Chloride as Treatment in Dementia Praecox.

    Canadian Medical Association journal·2010

    Area of Science:

    • Cardiovascular Surgery
    • Biomedical Engineering
    • Prosthetic Valve Technology

    Background:

    • Evaluating prosthetic valve performance is complex due to data diversity and inconsistent methodologies.
    • Preoperative cardiac anatomy and patient-specific factors are often not correlated with prosthetic outcomes.
    • Variations in surgical techniques, surgeon experience, and anticoagulation protocols introduce significant variability.

    Purpose of the Study:

    • To analyze the long-term clinical performance and characteristics of the caged ball valve.
    • To identify the advantages and disadvantages of caged ball valve technology based on extensive clinical data.
    • To provide insights into the durability, hemodynamic profile, and complications associated with this prosthetic device.

    Main Methods:

    • Review of extensive clinical data spanning over 20 years of caged ball valve use.
    • Analysis of hemodynamic performance, considering factors like central obstruction and turbulence.
    • Assessment of durability, thromboembolic rates, endocarditis incidence, and prosthetic thrombosis.
    • Evaluation of anatomical complications related to the valve's spatial requirements.

    Main Results:

    • The caged ball valve demonstrates durability with minimal ball variance since 1965.
    • Hemodynamic performance is adequate, but central obstruction leads to increased turbulence, hemolysis, and neointimal proliferation.
    • Thromboembolic rates are acceptable in anticoagulated patients; prosthetic thrombosis is rare in specific designs.
    • Significant anatomical complications arise from the valve's large size, particularly in patients with specific cardiac conditions.

    Conclusions:

    • The caged ball valve remains a clinically utilized option due to its durability and extensive historical data.
    • Design limitations necessitate careful patient selection to mitigate risks of hemodynamic compromise and anatomical issues.
    • Continued study and modification are implied by its long history and ongoing clinical use.

    Related Experiment Videos