[Bladder carcinoma associated with long-term treatment with cyclophosphamide for multiple myeloma (author's transl)]

A report is presented of a female patient who developed an extensive bladder carcinoma with severe hemorrhaging after many years of treatment with cyclophosphamide for multiple myeloma. The severe hemorrhage could only be controlled by drainage of the urine. The possible causes of the development of a second neoplasia, particularly of urinary bladder carcinoma following long-term therapy with cyclophosphamide, are discussed.