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Detection of lymphocyte subsets in renal graft biopsy by monoclonal antibodies

A Vangelista, G Frascá, A Nanni-Costa

    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association
    |January 1, 1983
    PubMed

    Monoclonal antibodies were used to study infiltrating cell subpopulations in 12 graft biopsy specimens taken from 12 patients during rejection episodes. A preponderance of T lymphocytes in the renal interstitium was observed in most cases, with a higher percentage of suppressor/cytotoxic cells. No correlation was documented between the type and severity of rejection and the percentage of the various infiltrating cells.

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