Related Experiment Videos
Captopril-induced deterioration of graft function in patients with a transplant renal artery stenosis
Abstract:
We evaluated nine captopril-treated patients with transplant renal artery stenosis. Captopril treatment always resulted in a dramatic decrease in renal function; in two patients complete anuria developed. Only in two patients with a stenosis in one out of two renal arteries was a satisfactory fall in blood pressure achieved. The mechanisms which may lead to these remarkable results will be discussed.