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Acyclovir therapy in herpes zoster infection. A practical guide
Transactions of the Ophthalmological Societies of the United Kingdom
|January 1, 1983
Summary
Acyclovir effectively treats skin rash and herpes zoster keratouveitis, outperforming topical steroids. Steroid treatment for herpes zoster keratouveitis can lead to adverse effects and recurrences.
Area of Science:
- Ophthalmology
- Virology
- Dermatology
Background:
- Herpes zoster keratouveitis is an ocular manifestation of the varicella-zoster virus.
- Skin rash is a common symptom associated with herpes zoster infections.
- Topical steroids are a common treatment for herpes zoster keratouveitis but have limitations.
Purpose of the Study:
- To evaluate the efficacy of acyclovir in treating herpes zoster-related skin rash and keratouveitis.
- To compare the effectiveness of acyclovir with topical steroids in managing herpes zoster keratouveitis.
Main Methods:
- Observational study comparing treatment outcomes.
- Analysis of patient data on disease progression and recurrence.
Main Results:
- Acyclovir demonstrated significant efficacy in resolving both skin rash and herpes zoster keratouveitis.
- Acyclovir proved superior to topical steroids in treating herpes zoster keratouveitis.
- Prolonged steroid use was associated with adverse effects and increased recurrence rates.
Conclusions:
- Acyclovir is a highly effective treatment for herpes zoster ophthalmic complications.
- Acyclovir offers a safer and more effective alternative to topical steroids for herpes zoster keratouveitis.