Intraocular pressure following aphakic transplants

Timolol maleate produced no significant difference in the initial mean intraocular pressure after keratoplasty using disparate-sized grafts (7.5 mm recipient, 8.0 mm donor). However, timolol did significantly reduce the number of eyes with an intraocular pressure elevation greater than 24 mm Hg. A series of patients with equal-sized donor and recipient cuts (8.0 mm) had initial intraocular pressure of 19.6 mm Hg. The normal intraocular pressure in these patients is thought to be due to superficial suturing, thereby preventing angle distortion.