Related Experiment Videos
Mitochondrial DNA-binding proteins that bind preferentially to supercoiled molecules containing the D-loop region of
Biochemical and Biophysical Research Communications
|November 30, 1983
Abstract:
From the bulk of the Xenopus laevis mitochondrial proteins insoluble in 1% Triton X-100 + 1M NaCl, we have isolated, by DNA-cellulose chromatography, a protein fraction enriched in DNA-binding proteins. This fraction contains proteins showing a specific affinity for supercoiled DNA molecules containing the mitochondrial DNA displacement-loop region, as measured by filter binding and competition assays.