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Updated: Aug 17, 2026

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
Published on: May 15, 2014
The role of vaccinia virus in the evolution of some human hemopathies
Abstract:
Six cases of severe hemopathy, detected following smallpox revaccination are described. Their onset was favoured by vaccinia virus-induced suppression of cell-mediated and humoral immunity. In two leukemia patients humoral immunity was present, but insufficient to assure protection of the diseased organisms, the outcome being fatal. The pancytopenia syndrome recorded in 4 patients with anergy caused by autoimmune mechanisms had different outcomes: favourable in 2 cases and fatal in the other 2 patients, who died within 4 years.
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