[Leukocyte migration inhibition reaction in melanoma]

Under study was the reaction of suppression of leucocytes migration in 28 patients with melanoma and in 15 healthy donors. In patients with the local neoplastic process the suppression of their lymphocytes migration under the melanoma extract influence was much more frequently observed and wos more significantly pronounced than in healthy donors and patients with metastases, especially in cases of wide tumor spread. Enhanced migration noted in a number of cases was associated with an unfavourable clinical course. Likewise, the enhanced migration was observed 2--3 weeks following resection of primary melanoma and in one case--at the end of the chemotherapy course.