Related Experiment Video
Updated: Aug 18, 2026

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
Published on: July 28, 2010
[Precancerous lesions of the colon and rectum]
Abstract:
We discussed significance of various kinds of precancerous lesions of the colon and rectum. Colonic adenoma was most important as a histogenetic background of colonic carcinoma, as it has been widely accepted. The first malignant transformation of adenoma seemed to occur at the relatively superficial layer of the central portion of adenoma in many cases. Growth rate of adenoma largely depended on cellular atypia. Six of twenty-seven patients with Peutz-Jeghers syndrome had advanced carcinoma and/or carcinoma in Peutz-Jeghers polyp. In general, malignant transformation in the polyp was higher in frequency in polyps more than 3.0 cm in the largest dimension. Significance of precancerous lesions in juvenile polyp, hyperplastic polyp, ulcerative colitis, Crohn's disease and radiation colitis was briefly presented.
More Related Videos
15:49Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
08:51Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
Related Concept Videos
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease II: Ulcerative Colitis
Diverticular Disease of the Colon