Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The stem cell system.

R Schofield

    Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
    |January 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Stem cells maintain tissue function through self-renewal. Their behavior is heavily influenced by the microenvironment, suggesting stem cell potential is not fixed to specific cell types.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Hot and dry conditions elevate grass pollen and sub-pollen particle concentrations in Melbourne, Australia.

    Environmental science: atmospheres·2025
    Same author

    Quantifying the reduction of airborne infectious viral load using a ventilated patient hood.

    The Journal of hospital infection·2023
    Same author

    Reviving through human hippocampal newborn neurons.

    L'Encephale·2021
    Same author

    Effectiveness of portable air filtration on reducing indoor aerosol transmission: preclinical observational trials.

    The Journal of hospital infection·2021
    Same author

    Image reconstruction: Part 1 - understanding filtered back projection, noise and image acquisition.

    Journal of cardiovascular computed tomography·2019
    Same author

    Image reconstruction in cardiovascular CT: Part 2 - Iterative reconstruction; potential and pitfalls.

    Journal of cardiovascular computed tomography·2019
    Same journal

    Corrigendum to "Ruyiping extract reduces lung metastasis in triple negative breast cancer by regulating macrophage polarization" [Biomed. Pharmacother. 141 (2021) 111883].

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
    Same journal

    Microfluidic human liver slices reveal antifibrotic effects of liraglutide via HSC deactivation and ECM remodeling.

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
    Same journal

    Corrigendum to "Targeting PD-L1 and disrupting Siglec-9 cooperatively potentiate macrophage phagocytosis of breast cancer via a trispecific macrophage engager (TriME)" [Biomed. Pharmacother. 200 (2026), 119609].

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
    Same journal

    Targeted attenuation of liver fibrosis using microbubble-enhanced protease-activated receptor 1 chimeric antigen receptor T cells.

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
    Same journal

    Euphol targets key oncogenic processes and promotes chemoprevention in organoid and In Vivo models of colorectal cancers.

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
    Same journal

    CAR-T cell therapy and oncolytic viruses: A synergic approach for advanced GI cancers.

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
    See all related articles

    Area of Science:

    • Cell biology
    • Developmental biology
    • Tissue engineering

    Background:

    • Stem cells are crucial for tissue maintenance and repair.
    • Their defining characteristic is self-renewal, producing daughter cells for tissue function.
    • The role of the microenvironment in stem cell regulation is increasingly recognized.

    Purpose of the Study:

    • To define the fundamental characteristics of stem cells.
    • To explore the influence of the microenvironment on stem cell behavior.
    • To present the stem cell niche hypothesis.

    Main Methods:

    • Review of existing evidence on stem cell biology.
    • Conceptualization of the stem cell niche hypothesis.
    • Postulation regarding the plasticity of stem cell potential.

    Related Experiment Videos

    Main Results:

    • Stem cell self-renewal is a fundamental property.
    • The microenvironment is essential for maintaining stem cell populations.
    • Stem cell properties can be influenced by the microenvironment, suggesting plasticity.

    Conclusions:

    • Stem cell function is dependent on the specific microenvironment or niche.
    • Cells may possess stem cell potential that can be activated by the appropriate microenvironment.
    • The concept of intrinsic stem cells may be less accurate than a model of environment-dependent stem cell potential.