Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pulmonary hypertensive diseases.

S Rounds, N S Hill

    Chest
    |March 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Pulmonary hypertension, a condition affecting pulmonary arterial pressure, can be primary or secondary. New vasodilators offer potential treatment, but more research is needed for early detection and understanding its harmful effects.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Ruminal ergovaline and volatile fatty acid dynamics: Association with poor performance and a key growth regulator in steers grazing toxic tall fescue.

    Environmental toxicology and pharmacology·2023
    Same author

    Prognostic Significance of Pulmonary Artery to Aorta Ratio and Other CT Markers in Pulmonary Fibrosis With and Without Emphysema.

    Lung·2021
    Same author

    Ten important articles on noninvasive ventilation in critically ill patients and insights for the future: A report of expert opinions.

    BMC anesthesiology·2017
    Same author

    The effects of ergot alkaloids on the breeding stallion reproductive system.

    Equine veterinary journal. Supplement·2013
    Same author

    Recognition of pulmonary hypertension in the rheumatology community: lessons from a Quality Enhancement Research Initiative.

    Clinical and experimental rheumatology·2013
    Same author

    Ergovaline and peramine production in endophyte-infected tall fescue: Independent regulation and effects of plant and endophyte genotype.

    Journal of chemical ecology·2013
    Same journal

    The effect of a two-day stay at high altitude (2500 m) on right ventricular afterload and oxygen delivery in patients with pulmonary vascular disease A randomized controlled crossover trial.

    Chest·2026
    Same journal

    A Comparative Study of Radiation Exposure in Conventional and Robotic Bronchoscopy.

    Chest·2026
    Same journal

    Independent Prognostic Contributions of Anti-Ro52 and Anti-MDA5 in Autoimmune-Associated Interstitial Lung Disease.

    Chest·2026
    Same journal

    Lung aeration and gas exchange in SGA or AGA infants with moderate-severe BPD: secondary analysis of the PATH-BPD study.

    Chest·2026
    Same journal

    Lung Cancer Incidence and Mortality after Negative Low-Dose CT Screening Results.

    Chest·2026
    Same journal

    Symptom prevalence and impact on lung cancer risk in the SUMMIT study.

    Chest·2026
    See all related articles

    Area of Science:

    • Cardiovascular Medicine
    • Pulmonary Medicine
    • Vascular Biology

    Background:

    • Pulmonary hypertension (PH) arises from primary vascular issues or secondary to cardiac/pulmonary diseases.
    • Reversibility of PH depends on vasoconstriction versus structural vessel changes.
    • Limited noninvasive methods for measuring pulmonary arterial pressure hinder early diagnosis.

    Purpose of the Study:

    • To review the current understanding of pulmonary hypertension pathogenesis and natural history.
    • To explore the potential role of new vasodilator therapies in treating PH.
    • To highlight the need for improved early detection and understanding of PH mechanisms.

    Main Methods:

    • Literature review of pulmonary vascular physiology and PH.
    • Discussion of clinical implications and treatment strategies.

    Related Experiment Videos

  • Analysis of the impact of vasodilator therapy on PH.

    • Main Results:

    • PH diagnosis often occurs at advanced stages due to measurement limitations.
    • Early hypoxic PH might be protective, but the threshold for harm is unknown.
    • Orally effective vasodilators present a new treatment avenue for primary and secondary PH.

    Conclusions:

    • Treatment of underlying conditions and severe PH with right ventricular dysfunction is indicated.
    • Further research is crucial to understand acute pulmonary vasoconstriction and sustained PH mechanisms.
    • Development of methods for early identification of mild PH is essential.