Ligandin in the human ovary

Human ovaries from different times during the menstrual cycle, pregnancy and the post-menopausal state were examined by immunohistochemistry using an antibody to ligandin. The results showed that antiligandin was localized to those cells producing steroids and probably acts as an intracellular transport protein but may also have an enzyme function in steroidogenesis. In demonstrating this relationship this study has indicated that antiligandin may be of value in the morphologic investigation of ovaries in conditions where there are assumed alterations in steroid production.