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[Post-traumatic nodular scleroderma].

M V Bonino, C Bianchi, O Bianchi

Medicina Cutanea Ibero-Latino-Americana

|January 1, 1983

Summary

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Localized scleroderma in children is rare, often linked to trauma or injections. This study presents two cases of nodular scleroderma potentially triggered by vaccinations or injuries, highlighting the need for further research into its causes.

Area of Science:

Pediatric Rheumatology
Dermatology
Pathology

Background:

Scleroderma is a rare collagen disease in children, accounting for less than 5% of cases.
Localized scleroderma is more common in pediatric patients, sometimes associated with trauma or injections.

Observation:

Two pediatric patients, aged 5 and 13, presented with nodular lesions on the thigh and buttock.
Lesions were larger than a palm, palpable, with irregular surfaces and imprecise borders. One case showed slight hyperpigmentation.
The onset of lesions followed antitetanical vaccination and a thorn puncture, with evolution over 2-3 years.

Findings:

Histological examination revealed extensive fibrohyalinosis affecting the deep dermis and superficial hypodermis.
Laboratory studies yielded no significant findings.

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Clinical and histological features differed from scleroderma-like reactions to vitamin K, B12, norhydroxprogesterone, and anti-tetanic serum, as well as paniculitis artefacta and linear morphea.

Implications:

The findings suggest a potential link between prior trauma, including vaccinations, and the development of nodular scleroderma in children.
Distinguishing this form from other sclerotic conditions is crucial for accurate diagnosis and management.
Further investigation is warranted to elucidate the specific mechanisms connecting trauma and nodular scleroderma onset.