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[3 osteosarcoma therapy dropouts. Clinical cases].

J Knispel, R Thiel, H Wallis

    Onkologie
    |December 1, 1983
    PubMed
    Summary
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    Three young male osteogenic sarcoma patients refused chemotherapy due to intolerable side effects and fear of medical procedures. Disturbed family backgrounds and personality traits like early independence influenced their decisions.

    Area of Science:

    • Oncology
    • Adolescent Medicine
    • Psychology

    Background:

    • Osteogenic sarcoma treatment often involves aggressive chemotherapy.
    • Adherence to treatment plans is crucial for patient outcomes.
    • Understanding patient refusal factors is vital for personalized care.

    Observation:

    • Three male patients (late adolescence/young adulthood) with osteogenic sarcoma refused the full COSS 80 chemotherapy protocol.
    • Patients reported disturbed family situations, early independence, and high sociability.
    • Key reasons for refusal included perceived intolerability of chemotherapy side effects and significant fear of medical procedures like injections.

    Findings:

    • Patient refusal of cancer treatment can be multifactorial, influenced by psychological and social factors.

    Related Experiment Videos

  • Personality traits such as autonomy and low self-control may correlate with treatment non-adherence.
  • Fear of medical interventions and side effect management are significant barriers to chemotherapy completion.

    • Implications:

    • This case series highlights the need for tailored patient support and psychological interventions in osteogenic sarcoma treatment.
    • Healthcare providers should address patient fears and side effect concerns proactively.
    • Further research into the psychological and social determinants of cancer treatment adherence is warranted.