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[3 osteosarcoma therapy dropouts. Clinical cases]
Abstract:
We report on 3 cases of male late-adolescent/young-adult osteogenic sarcoma patients who refused complete chemical therapy according to the treatment plan "COSS 80". They all originated from disturbed family situations. Characteristic was their early independence and autonomy, dominance tendency, low level of self control, and high level of sociability. Primary motivation for refusal was the experienced intolerability of the chemotherapeutical side-effects and extreme fear of medical procedures (e.g. injections).
Insights
Three young male osteogenic sarcoma patients refused chemotherapy due to intolerable side effects and fear of medical procedures. Disturbed family backgrounds and personality traits like early independence influenced their decisions.
Area of Science:
- Oncology
- Adolescent Medicine
- Psychology
Background:
- Osteogenic sarcoma treatment often involves aggressive chemotherapy.
- Adherence to treatment plans is crucial for patient outcomes.
- Understanding patient refusal factors is vital for personalized care.
Observation:
- Three male patients (late adolescence/young adulthood) with osteogenic sarcoma refused the full COSS 80 chemotherapy protocol.
- Patients reported disturbed family situations, early independence, and high sociability.
- Key reasons for refusal included perceived intolerability of chemotherapy side effects and significant fear of medical procedures like injections.
Findings:
- Patient refusal of cancer treatment can be multifactorial, influenced by psychological and social factors.
- Personality traits such as autonomy and low self-control may correlate with treatment non-adherence.
- Fear of medical interventions and side effect management are significant barriers to chemotherapy completion.
Implications:
- This case series highlights the need for tailored patient support and psychological interventions in osteogenic sarcoma treatment.
- Healthcare providers should address patient fears and side effect concerns proactively.
- Further research into the psychological and social determinants of cancer treatment adherence is warranted.